what trans do you have now? c6 3 speed or AOD? you want to go to E4OD?
if you're going from c6 to AOD I dont think there are any mods required,The AOD is controlled by the same vacuum setup that your c6 would be, the shift linkage also uses a 3 foreword position setup so your column isn't affected, I would just double check when you get one that it will mate up with your transfer case.
going from c6 or AOD to E4OD requires a little extra work.